Download PLR Content Directory Barbados: July 2010

Wednesday, 28 July 2010

Clobex

Clobex is a brand name of clobetasol topical, approved by the FDA in the following formulation(s):

CLOBEX (clobetasol propionate - lotion; topical)

Manufacturer: GALDERMA LABS LP

Approval date: July 24, 2003

Strength(s): 0.05% ^[RLD]^[AB]

CLOBEX (clobetasol propionate - shampoo; topical)

Manufacturer: GALDERMA LABS

Approval date: February 5, 2004

Strength(s): 0.05% ^[RLD]^[AB]

CLOBEX (clobetasol propionate - spray; topical)

Manufacturer: GALDERMA LABS LP

Approval date: October 27, 2005

Strength(s): 0.05% ^[RLD]^[AT]

Has a generic version of Clobex been approved?

A generic version of Clobex has been approved by the FDA. However, this does not mean that the product will necessarily be commercially available - possibly because of drug patents and/or drug exclusivity. The following products are equivalent to Clobex and have been approved by the FDA:

clobetasol propionate lotion; topical

Manufacturer: ACTAVIS MID ATLANTIC

Approval date: December 4, 2008

Strength(s): 0.05% ^[AB]

clobetasol propionate shampoo; topical

Manufacturer: ACTAVIS MID ATLANTIC

Approval date: June 7, 2011

Strength(s): 0.05% ^[AB]

clobetasol propionate spray; topical

Manufacturer: PADDOCK LLC

Approval date: June 16, 2011

Strength(s): 0.05% ^[AT]

Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Clobex. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

Related Patents

Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.

Formulation containing a carrier, active ingredient, and surfactant for treating skin disorders
Patent 5,972,920
Issued: October 26, 1999
Inventor(s): Seidel; William E.
Assignee(s): Dermalogix Partners, Inc.
One or more formulations for treating psoriasis and other skin disorders characterized by redness, itching, flaking, scaling, and plaque-type growth. The formulation includes a carrier component, one or more active ingredient components, and a surfactant component. The carrier preferably includes an alcohol in substantially equal volume with isopropyl myristate. The active ingredient component preferably includes a superpotent or high-potency corticosteroid such as clobetasol propionate, an anti-flaking ingredient such as zinc pyrithione, or a combination of the two. It may also include an anti-fungal compound. The surfactant component preferably includes an alkyl sulfate such as sodium lauryl sulfate. The formulations made by applied topically either in spray form or as a direct-contact liquid.
Patent expiration dates:
- February 12, 2018
  ✓
  Drug product

Composition and method for treatment of psoriasis
Patent 5,990,100
Issued: November 23, 1999
Inventor(s): Rosenberg; E. William & Glenn; Thomas M. & Skinner, Jr.; Robert B. & Noah; Patricia W.
Assignee(s): Panda Pharmaceuticals, L.L.C.
The University of Tennessee Research Corporation
Pharmaceutical compositions and methods for use in the treatment of psoriasis, having isopropyl myristate as a first active ingredient and a different anti-psoriatic agent as a second active ingredient; preferably they are combined in the same pharmaceutical composition.
Patent expiration dates:
- March 24, 2018
  ✓
  Patent use: TWICE DAILY TOPICAL TREATMENT OF MODERATE TO SEVERE PLAQUE PSORIASIS.
  ✓
  Drug product

Topically applicable O/W emulsions having high glycol content and at least one biologically active agent
Patent 6,106,848
Issued: August 22, 2000
Inventor(s): Preuilh; Isabelle & Willcox; Nathalie
Assignee(s): Centre International de Recherches Dermatologiques
Stable, topically applicable oil-in-water bioaffecting emulsions having intermediate viscosity, characteristically ranging from 3 to 10 Pa.multidot.s, comprise (a) from 30% to 50% by weight of at least one pro-penetrating glycol, (b) at least one emulsifying agent, advantageously an anionic amphiphilic polymer, and (c) at least one biologically active agent, for example an active agent that modulates skin differentiation and/or proliferation and/or pigmentation, an anti-inflammatory, an antibacterial, an antifungal, etc.
Patent expiration dates:
- September 22, 2017

Foaming composition for washing and treating hair and/or scalp based on an active principle
Patent 7,316,810
Issued: January 8, 2008
Inventor(s): Preuilh; Isabelle & Guise; Anne-Emmanuelle & Willcox; Nathalie
Assignee(s): Galderma S.A.
The invention concerns a foaming composition for washing and treating hair and/or scalp essentially characterized in that it contains in an aqueous medium: at least an active principle selected among corticoids and retinoids; at least an anionic surfactant; at least an amphoteric surfactant; and a pro-penetrating agent.
Patent expiration dates:
- June 17, 2019
  ✓
  Drug product

Foaming compositions for hair care
Patent 7,700,081
Issued: April 20, 2010
Inventor(s): Preuilh; Isabelle & Guise; Anne-Emmanuelle & Willcox; Nathalie
Assignee(s): Galderma S.A.
The invention concerns a foaming composition for washing and treating hair and/or scalp essentially characterised in that it contains in an aqueous medium: at least an active principle selected among corticoids and retinoids; at least an anionic surfactant; at least an amphoteric surfactant; and a pro-penetrating agent.
Patent expiration dates:
- January 3, 2022
  ✓
  Patent use: TOPICAL TREATMENT OF SCALP PSORIASIS

Foaming composition for washing and treating hair and/or scalp based on an active principle
Patent 8,066,975
Issued: November 29, 2011
Inventor(s): Preuilh; Isabelle & Guise; Anne-Emmanuelle & Willcox; Nathalie
Assignee(s): Galderma S.A.
The invention concerns a foaming composition for washing and treating hair and/or scalp essentially characterized in that it contains in an aqueous medium: at least an active principle selected among corticoids and retinoids; at least an anionic surfactant; at least an amphoteric surfactant; and a pro-penetrating agent.
Patent expiration dates:
- June 17, 2019
  ✓
  Drug product

Foaming compositions for hair care
Patent 8,066,976
Issued: November 29, 2011
Inventor(s): Preuilh; Isabelle & Guise; Anne-Emmanuelle & Willcox; Nathalie
Assignee(s): Galderma S.A.
The invention concerns a foaming composition for washing and treating hair and/or scalp essentially characterised in that it contains in an aqueous medium: at least an active principle selected among corticoids and retinoids; at least an anionic surfactant; at least an amphoteric surfactant; and a pro-penetrating agent.
Patent expiration dates:
- June 17, 2019
  ✓
  Drug product

Saturday, 24 July 2010

Famotidin ratiopharm

Famotidin-ratiopharm may be available in the countries listed below.

Ingredient matches for Famotidin-ratiopharm

Famotidine

Famotidine is reported as an ingredient of Famotidin-ratiopharm in the following countries:

Austria

Germany

International Drug Name Search

Thursday, 22 July 2010

Robinul Tablets

Pronunciation: GLYE-koe-PIR-oh-late
Generic Name: Glycopyrrolate
Brand Name: Robinul and Robinul Forte

Robinul is used for:

Treating peptic ulcers in combination with other medicines. It may also be used for other conditions as determined by your doctor.

Robinul is an anticholinergic. It works by blocking the activity of a certain substance (acetylcholine) in the body, which decreases stomach acid secretion.

Do NOT use Robinul if:

you are allergic to any ingredient in Robinul

you have glaucoma, urinary blockage (eg, inability to urinate), certain stomach or bowel problems (eg, stomach or bowel blockage, bowel paralysis, severe ulcerative colitis, toxic megacolon), myasthenia gravis, or heart problems caused by bleeding

you are taking a solid oral doseform of potassium (eg, a tablet)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Robinul:

Some medical conditions may interact with Robinul. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have nerve problems (eg, autonomic neuropathy), prostate problems, trouble urinating, liver problems, kidney problems, increased pressure in the eyes, an overactive thyroid, or a family history of glaucoma

if you have heart problems (eg, coronary heart disease, heart failure), a fast or irregular heartbeat, or high blood pressure

if you have stomach or bowel problems (eg, ulcerative colitis), hiatal hernia along with reflux disease, constipation or diarrhea, or if you have an ileostomy or colostomy

if you are in poor health

Some MEDICINES MAY INTERACT with Robinul. Tell your health care provider if you are taking any other medicines, especially any of the following:

Solid oral potassium products (eg, tablets) because the risk of stomach or bowel irritation may be increased by Robinul

Anticholinergics (eg, benztropine), phenothiazines (eg, chlorpromazine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Robinul's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Robinul may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Robinul:

Use Robinul as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Robinul by mouth with or without food.

If you miss a dose of Robinul, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Robinul.

Important safety information:

Robinul may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Robinul with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Robinul; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

Drinking fluids, maintaining good oral hygiene, and sucking on hard sugarless candy can help relieve dry mouth.

Do not become overheated in hot weather or while you are being active; heatstroke may occur.

Use Robinul with extreme caution if you have a fever because heatstroke caused by decreased sweating may occur.

Robinul may make your eyes more sensitive to sunlight. It may help to wear sunglasses.

Use Robinul with caution in the ELDERLY; they may be more sensitive to its effects.

Caution is advised when using Robinul in CHILDREN; they may be more sensitive to its effects.

Robinul should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.

PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Robinul while you are pregnant. It is not known if Robinul is found in breast milk. Robinul may decrease milk production. If you are or will be breast-feeding while you use Robinul, check with your doctor. Discuss any possible risks to your baby, as well as any questions or concerns about this information.

Possible side effects of Robinul:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Bloated feeling; blurred vision; constipation; decreased sweating; dizziness; drowsiness; dry mouth; dry skin; enlarged pupils; headache; loss of taste; nausea; nervousness; sleeplessness; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; confusion; decreased sexual ability; diarrhea; difficulty focusing the eyes; difficulty urinating; excitement; fainting; fast, slow, or irregular heartbeat; seizures; severe or persistent dizziness, light-headedness, or headache; shortness of breath; unusual weakness; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Robinul side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; difficulty breathing; enlarged pupils; excessive thirst; flushed, hot, dry skin; muscle weakness; nausea; paralysis; restlessness; seizures; severe dry mouth; unusual dizziness or drowsiness; vomiting.

Proper storage of Robinul:

Store Robinul at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Robinul out of the reach of children and away from pets.

General information:

If you have any questions about Robinul, please talk with your doctor, pharmacist, or other health care provider.

Robinul is to be used only by the patient for whom it is prescribed. Do not share it with other people.

If your symptoms do not improve or if they become worse, check with your doctor.

Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Robinul. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

More Robinul resources

Robinul Side Effects (in more detail)
Robinul Dosage
Robinul Use in Pregnancy & Breastfeeding
Drug Images
Robinul Drug Interactions
Robinul Support Group
0 Reviews for Robinul - Add your own review/rating

Compare Robinul with other medications

Anesthesia
Peptic Ulcer

Docusate Salts

Class: Cathartics and Laxatives
ATC Class: A06AA
VA Class: GA205
CAS Number: 128-49-4
Brands: Colace, Correctol, Diocto, Docusoft S, DOK, DOS, Ex-Lax Stool Softener, Fleet Sof-Lax, Gentlax S, Peri-Colace S, Phillips’, Senokot S, Surfak, Therevac Plus Enema, Therevac S.B. Enema

Introduction

Stool softeners (emollients); anionic, surface-active agents (surfactants) that have emulsifying and wetting properties.^b ^c

Uses for Docusate Salts

Constipation

Used as stool softeners (emollients) to relieve occasional constipation.^a ^c ^e

Preferred to bulk-forming laxatives to ease evacuation of feces in constipation associated with hard, dry stools.^c

Considered the treatment of choice by many clinicians for childhood constipation associated with hard, dry stools and to be safer and more efficacious than mineral oil for conditions in which straining at defecation is to be avoided.^c

Particularly useful prophylactically for softening stools and preventing painful defecation in patients who have or are about to undergo hemorrhoid surgery or who have other anorectal disorders or when it is desirable to avoid straining at defecation (e.g., following abdominal surgery, recent rectal surgery, or myocardial infarction; in patients with vascular diseases, diseases of the anus or rectum, or hernias; immediately postpartum).^c ^e

Used as stool softeners for constipation associated with stricture of the colon.^c

Used to soften fecal impactions.^c Safer and more efficacious than mineral oil.^c After softening the impacted feces with a stool softener, stimulant or saline laxatives may be administered rectally to evacuate the impacted colon.^c

Used in combination with stimulant laxatives (e.g., senna, bisacodyl) for long-term management of opiate-induced constipation.^e

Docusate Salts Dosage and Administration

Administration

Docusate salts are administered orally and the sodium salt also is administered rectally.^a ^b

Adequate fluid intake facilitates stool softening.^e

Oral Administration

Administer orally.^a ^b

Dilution

Oral liquids (not syrups) of docusate sodium should be diluted with 120 mL of milk, fruit juice, or infant formula to mask their bitter taste.^b

Rectal Administration

The sodium salt of docusate may be administered rectally.^b

Dosage

Administered in doses only large enough to produce softening of the stools.^b

Oral dosage varies widely according to the severity of the condition and the response of the patient and should be adjusted to individual response.^b

Pediatric Patients

Constipation

May be administered in divided doses, but usually one bedtime dose is sufficient.^b

Initially, doses at the higher end of the dosage ranges may be required.^b

Oral

Children <2 years of age: Usually, 25 mg (range: 20–50 mg) daily.^b ^e

Children 2–12 years of age: Usually, 50–150 mg daily.^b ^e

Children >12 years of age: Usually, 50–360 mg daily.^b ^e

Oral, Alternative Dosing (e.g., Liquid Formulations)

Children <3 years of age: 10–40 mg daily.^e

Children 3–6 years of age: 20–60 mg daily.^b ^e

Children 6–12 years of age: 40–150 mg daily.^b ^e

Rectal

Add 50–100 mg of docusate sodium as an oral liquid (not syrup) to saline or oil retention enemas for rectal use.^b

Adults

Constipation

Oral

Usually, 50–360 mg daily.^b ^e

Oral, Alternative Dosing (e.g., Liquid Formulations)

50–500 mg daily.

Rectal

Add 50–100 mg of docusate sodium as an oral liquid (not syrup) to saline or oil retention enemas for rectal use.^b

Special Populations

Hepatic Impairment

No specific dosage recommendations for hepatic impairment.^a ^b

Renal Impairment

No specific dosage recommendations for renal impairment.^a ^b

Geriatric Patients

No specific geriatric dosage recommendations.^a

Cautions for Docusate Salts

Contraindications

In acute abdominal pain, nausea, vomiting, or other symptoms of appendicitis or undiagnosed abdominal pain.^c ^e

Warnings/Precautions

General Precautions

Chronic Use or Overdosage

Chronic use or overdosage of laxatives may produce persistent diarrhea, hypokalemia, loss of essential nutritional factors, and dehydration.^c

Mainly associated with stimulant laxatives, but consider the possibility that laxative dependence, chronic constipation, and loss of normal bowel function could occur with any laxative during long-term use.^c

Use of Fixed Combination

When used in fixed combination with other agents, consider the cautions, precautions, and contraindications associated with the concomitant agents.

Common Adverse Effects

Adverse effects are rare.^c Occasionally, mild, transitory GI cramping pains, diarrhea, or rashes may occur.^c ^e Irritation of the throat following oral administration of docusate sodium solutions.^c

Interactions for Docusate Salts

GI Drug Absorption

Docusate salts, which are surface-active agents (surfactants), theoretically may enhance the absorption of many orally administered drugs.^c ^e The surfactant properties potentially could facilitate transport of other substances across cell walls.^e

Some clinicians recommend that stool softeners not be administered concurrently with any oral drugs having low therapeutic indices.

Specific Drugs

Drug	Interaction	Comments
Aspirin	Potentiates aspirin-induced intestinal mucosal damage^c ^e	Use concomitantly with caution^e
Mineral oil	Increased GI absorption of mineral oil^c ^e	Avoid concomitant use^c

Docusate Salts Pharmacokinetics

Absorption

Bioavailability

Not determined, but docusate salts appear to be absorbed to some extent in the duodenum and jejunum and subsequently excreted in bile.^b

Extent of absorption following rectal administration of docusate sodium is unknown.^b

Onset

Fecal softening generally occurs within 1–3 days.^b

Generally produces a bowel movement in 12–72 hours, but occasionally may take up to 3–5 days.^a ^e

Duration

About 72 hours.^e

Stability

Storage

Oral

Capsules

Capsules of the docusate salts should be stored in tight containers at 25°C (may be exposed to 15–30°C) .^a ^b ^d Storage of liquid-filled capsules also should include a dry place.^d

Solutions and Syrups

Solutions in tight containers.^b ^d

Syrups in tight, light-resistant containers.^b ^d

Tablets

Well-closed containers.^d

ActionsActions

Anionic, surface-active (surfactant) agents that have emulsifying and wetting properties.^b

Soften fecal material and ease defecation by lowering surface tension at the oil-water interface of fecal material, permitting water and lipids to penetrate.^c

Laxative properties may result from stimulation of electrolyte and water secretion in the colon.^c

May alter the permeability of colonic mucosal cells and mediate active ion secretion thereby producing net fluid accumulation and laxative action.^c

Advice to Patients

Importance of adequate fluid intake to facilitate stool softening.^e

Importance of not using laxative products for a period longer than 1 week unless directed by a clinician.^a ^c

Importance of informing clinicians before use if abdominal pain, nausea, or vomiting is present or if a sudden change in bowel habits that persists over a period of 2 weeks has been noticed.^a ^c

Importance of informing clinicians before use if currently taking mineral oil.^a

Importance of stopping use and informing a clinician if rectal bleeding occurs or a bowel movement fails to occur after use.^a These could be signs of a serious condition.^a

Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs as well as any concomitant illnesses.

Importance of women informing clinicians if they are or plan to become pregnant or plan to breast-feed.

Importance of informing patients of other important precautionary information. (See Cautions.)

Preparations

Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.

* available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name

Docusate Calcium (Dioctyl Calcium Sulfosuccinate)
Routes	Dosage Forms	Strengths	Brand Names	Manufacturer
Oral	Capsules, liquid-filled	240 mg*	Surfak Liqui-Gels (with parabens)	Pfizer

* available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name

Docusate Sodium (Dioctyl Sodium Sulfosuccinate, DOSS, DSS)
Routes	Dosage Forms	Strengths	Brand Names	Manufacturer
Bulk	Powder*
Oral	Capsules, liquid-filled	50 mg	Colace (with propylene glycol)	Purdue
		100 mg*	Colace (with parabens and propylene glycol)	Purdue
			Correctol Soft Gels (with propylene glycol)	Schering-Plough
			Docusoft S Softgels	G&W
			DOK	Major
			DOS Softgels	IVAX
			Fleet Sof-Lax	Fleet
			Phillips’ Liqui-Gels (with parabens and propylene glycol)	Novartis
		250 mg*	DOK	Major
			DOS Softgels	IVAX
	Solution	10 mg/mL*	Colace Liquid (with parabens and propylene glycol; with calibrated dropper)	Purdue
			Diocto Liquid	Alpharma, Major, Rugby, IVAX
			Docusate Sodium Liquid	Morton Grove, Pharmaceutical Associates
	Syrup	16.7 mg/5 mL	Docusate Sodium Syrup	Roxane
		20 mg/5 mL*	Colace Syrup (with ≤1% alcohol and parabens)	Purdue
			Diocto Syrup	Alpharma, Rugby, IVAX
			Docusate Sodium Syrup	Morton Grove, Pharmaceutical Associates
			DOK Syrup	Major
	Tablets	100 mg*	Ex-Lax Stool Softener Caplets (with methylparaben)	Novartis
Rectal	Suspension	283 mg/4 mL	Therevac S.B. Enema (with glycerin and green soap)	Jones Pharma

Docusate Sodium Combinations
Routes	Dosage Forms	Strengths	Brand Names	Manufacturer
Oral	Tablets	50 mg with Standardized Senna Concentrate (sennosides 8.6 mg)	Gentlax S	Purdue Frederick
			Peri-Colace	Purdue
			Senokot S	Purdue Frederick
Rectal	Suspension	283 mg/4 mL with Benzocaine 20 mg/4 mL	Therevac Plus Enema (with glycerin and green soap)	Jones Pharma

Comparative Pricing

This pricing information is subject to change at the sole discretion of DS Pharmacy. This pricing information was updated 03/2011. Actual costs to patients will vary depending on the use of specific retail or mail-order locations and health insurance copays.

Senna Lax 8.6MG Tablets (QUALITEST): 1000/$39.99 or 3000/$99.97

Disclaimer

This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.

The American Society of Health-System Pharmacists, Inc. and Drugs.com represent that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. and Drugs.com make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. and Drugs.com do not endorse or recommend the use of any drug. The information is not a substitute for medical care.

AHFS Drug Information. © Copyright, 1959-2011, Selected Revisions May 2006. American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland 20814.

References

a. Purdue Products, L.P. Colace(docusate sodium) prescribing information. Stamford, CT: 2003.

b. AHFS Drug Information 2004. McEvoy, GK, ed. Stool softeners. Bethesda, MD: American Society of Health-System Pharmacists; 2004:2780-81.

c. AHFS Drug Information 2004. McEvoy, GK, ed. Cathartics and laxatives general statement. Bethesda, MD: American Society of Health-System Pharmacists; 2004:2769-73

d. The United States pharmacopeia, 27th rev, and The national formulary, 22nd ed. Rockville, MD: The United States Pharmacopeial Convention, Inc; 2004:653-8.

e. American Pharmaceutical Association. Handbook of nonprescriptin drugs. 14th ed. Washington, DC: American Pharmaceutical Association; 2004:378,381.

Wednesday, 14 July 2010

betaxolol Ophthalmic

be-TAX-oh-lol

Commonly used brand name(s)

In the U.S.

Betoptic S

Available Dosage Forms:

Solution

Suspension

Therapeutic Class: Antiglaucoma

Pharmacologic Class: Beta-Adrenergic Blocker, Cardioselective

Uses For betaxolol

Betaxolol is used alone or together with other medicines to treat increased pressure in the eye that is caused by open-angle glaucoma or a condition called ocular (eye) hypertension. betaxolol is a beta-blocker .

betaxolol is available only with your doctor's prescription .

Before Using betaxolol

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For betaxolol, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to betaxolol or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatrics-specific problems that would limit the usefulness of betaxolol in children .

Geriatric

Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of betaxolol in the elderly .

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking betaxolol, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using betaxolol with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Albuterol

Amiodarone

Arformoterol

Bambuterol

Bitolterol

Broxaterol

Clenbuterol

Clonidine

Colterol

Diltiazem

Disopyramide

Dronedarone

Fenoldopam

Fenoterol

Formoterol

Hexoprenaline

Indacaterol

Isoetharine

Levalbuterol

Metaproterenol

Pirbuterol

Procaterol

Reproterol

Rimiterol

Ritodrine

Salmeterol

Terbutaline

Tretoquinol

Tulobuterol

Verapamil

Using betaxolol with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acarbose

Aceclofenac

Acemetacin

Acetohexamide

Alclofenac

Alfuzosin

Amlodipine

Apazone

Arbutamine

Benfluorex

Benoxaprofen

Bromfenac

Bufexamac

Bunazosin

Carprofen

Chlorpropamide

Clometacin

Clonixin

Dexketoprofen

Diclofenac

Diflunisal

Digoxin

Dipyrone

Doxazosin

Droxicam

Etodolac

Etofenamate

Felbinac

Felodipine

Fenbufen

Fenoprofen

Fentiazac

Floctafenine

Flufenamic Acid

Flurbiprofen

Gliclazide

Glimepiride

Glipizide

Gliquidone

Glyburide

Guar Gum

Ibuprofen

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Indoprofen

Insulin

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Insulin Glulisine

Insulin Lispro, Recombinant

Isoxicam

Ketoprofen

Ketorolac

Lacidipine

Lercanidipine

Lornoxicam

Manidipine

Meclofenamate

Mefenamic Acid

Meloxicam

Metformin

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Miglitol

Moxisylyte

Nabumetone

Naproxen

Nicardipine

Nifedipine

Niflumic Acid

Nilvadipine

Nimesulide

Nimodipine

Nisoldipine

Nitrendipine

Oxaprozin

Oxyphenbutazone

Phenoxybenzamine

Phentolamine

Phenylbutazone

Pirazolac

Piroxicam

Pirprofen

Pranidipine

Prazosin

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Proquazone

Repaglinide

St John's Wort

Sulindac

Suprofen

Tamsulosin

Tenidap

Tenoxicam

Terazosin

Tiaprofenic Acid

Tolazamide

Tolbutamide

Tolmetin

Trimazosin

Troglitazone

Urapidil

Zomepirac

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of betaxolol

Shake the medicine well just before each use .

To use the eye drops (solution):

First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink. Keep the eyes closed and apply pressure to the inner corner of the eye with your finger for 1 or 2 minutes to allow the medicine to be absorbed by the eye.

Immediately after using the medicine, wash your hands to remove any medicine that may be on them.

To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed. Serious damage to the eye and possible loss of vision may result from using contaminated eye medicines .

If your doctor ordered two different eye medicines to be used together, wait at least 10 minutes before using the second medicine. This will help prevent the second medicine from “washing out” the first one .

Dosing

The dose of betaxolol will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of betaxolol. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For ophthalmic solution dosage form (eye drops):
- For glaucoma or ocular hypertension:
  - Adults and children—One drop in the affected eye(s) two times a day .

Missed Dose

If you miss a dose of betaxolol, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using betaxolol

It is very important that your doctor check your progress at regular visits to make sure betaxolol is working properly and to check for unwanted effects .

If itching, redness, swelling, or other signs of eye or eyelid irritation occur, stop using betaxolol and check with your doctor. These signs may mean that you are allergic to betaxolol .

Betaxolol may cause heart failure in some patients. Check with your doctor right away if you are having chest pain or discomfort; dilated neck veins; extreme fatigue; irregular breathing; an irregular heartbeat; shortness of breath; swelling of the face, fingers, feet, or lower legs; weight gain; or wheezing .

betaxolol may cause changes in your blood sugar levels. Also, betaxolol may cover up signs of low blood sugar, such as a rapid pulse rate. Check with your doctor if you have these problems or if you notice a change in the results of your blood or urine sugar tests .

Make sure any doctor or dentist who treats you knows that you are using betaxolol. You may need to stop using betaxolol several days before having surgery .

betaxolol Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Pain in the eye

Rare

Blistering, peeling, or loosening of skin

blue lips, fingernails, or skin

blurred vision

change in color vision

chest pain or discomfort

chills

cough

crusting of eyelashes

decreased urine output

decreased vision

diarrhea

different size pupils of the eyes

difficulty in breathing, chewing, swallowing, or talking

difficulty seeing at night

dilated neck veins

double vision

drainage from eyes

drooping eyelids

extreme fatigue

fast, slow, or irregular heartbeat

feeling of having something in the eye

hives

increased sensitivity of eyes to sunlight

irregular, fast or slow, or shallow breathing

irritation or inflammation of eye

itching, dryness of eyes

itching skin

joint or muscle pain

lightheadedness, dizziness, or fainting

muscle weakness

noisy breathing

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

red skin lesions, often with a purple center

red, irritated eyes

severe tiredness

shortness of breath

skin rash

sore throat

sores, ulcers, or white spots in mouth or on lips

sweating

swelling of eyelids

swelling of face, fingers, feet, or lower legs

tearing

thickened mucous from lungs

tightness in chest

troubled breathing

unusual tiredness or weakness

weight gain

wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare

Bad, unusual, or unpleasant (after) taste

change in sense of smell

change in taste

discouragement

feeling of constant movement of self or surroundings

feeling sad or empty

hair loss

headaches

irritability

lack of appetite

loss of interest or pleasure

redness, swelling, or soreness of tongue

sensation of spinning

sleeplessness

tiredness

trouble concentrating

trouble sleeping

unable to sleep

unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More betaxolol Ophthalmic resources

Betaxolol Ophthalmic Use in Pregnancy & Breastfeeding
Betaxolol Ophthalmic Drug Interactions
Betaxolol Ophthalmic Support Group
0 Reviews for Betaxolol Ophthalmic - Add your own review/rating

betaxolol ophthalmic Concise Consumer Information (Cerner Multum)

Betoptic Prescribing Information (FDA)

Betoptic S Prescribing Information (FDA)

Betoptic S eent Monograph (AHFS DI)

Compare betaxolol Ophthalmic with other medications

Glaucoma, Open Angle
Intraocular Hypertension

Wednesday, 7 July 2010

Sertralina Cinfa

Sertralina Cinfa may be available in the countries listed below.

Ingredient matches for Sertralina Cinfa

Sertraline

Sertraline is reported as an ingredient of Sertralina Cinfa in the following countries:

Portugal

Sertraline hydrochloride (a derivative of Sertraline) is reported as an ingredient of Sertralina Cinfa in the following countries:

Spain

International Drug Name Search

Sunday, 4 July 2010

Bisco-Lax

Generic Name: bisacodyl (bis AK oh dil)

Brand Names: Alophen, Bisac-Evac, Bisco-Lax, Carters Little Pills, Correctol, Doxidan Tablet, Dulcolax Laxative, Evac-U-Gen, Ex-lax Ultra, Feen-A-Mint, Fleet Bisacodyl, Gen Lax, Gentlax Tablet, Gentle Laxative, Laxative Gentle Suppositories, Magic Bullet, Modane, Veracolate

What is Bisco-Lax (bisacodyl)?

Bisacodyl is a laxative that stimulates bowel movements.

Bisacodyl is used to treat constipation or to empty the bowels before surgery, colonoscopy, x-rays, or other intestinal medical procedure.

Bisacodyl may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Bisco-Lax (bisacodyl)?

Do not use bisacodyl if you have stomach (abdominal) pain, nausea, or vomiting, unless directed by a doctor.

If you notice a sudden change in bowel habits that persists over a period of 2 weeks, consult your healthcare provider before using a laxative.

Bisacodyl products should not be used for longer than one week, unless otherwise directed by your healthcare provider.

Rectal bleeding or failure to have a bowel movement after use of a laxative may indicate a more serious condition. Stop using bisacodyl and contact your healthcare provider.

What should I discuss with my healthcare provider before using Bisco-Lax (bisacodyl)?

You should not use this medication if you are allergic to bisacodyl, or if you have:

severe stomach pain, nausea, or vomiting;

a perforated bowel;

a blockage in your intestines;

fructose or galactose intolerance;

an allergy to yellow food dye;

severe constipation or dehydration;

inflammatory bowel disease, toxic megacolon; or

a sudden change in bowel habits lasting 2 weeks or longer.

People with eating disorders (such as anorexia or bulimia) should not use this medication without the advice of a doctor.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use bisacodyl:

kidney disease;

trouble swallowing;

a history of bowel obstruction, diverticulitis, ulcerative colitis, or other intestinal disorder; or

if you are taking a diuretic ("water pill").

Do not use bisacodyl without telling your doctor if you are pregnant. Do not use bisacodyl without telling your doctor if you are breast-feeding a baby. Do not give this medication to a child without the advice of a doctor.

When used to treat constipation, bisacodyl is only part of a complete program of treatment that may also include diet and exercise. Follow your doctor's instructions very closely.

How should I use Bisco-Lax (bisacodyl)?

Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.

For best results, take bisacodyl on an empty stomach, or at bedtime. Do not crush, chew, or break the enteric-coated tablet. Swallow it whole. The enteric-coated pill has a special coating to protect your stomach. Breaking the pill could damage this coating. Do not take a bisacodyl rectal (enema or suppository) by mouth. It is for use only in your rectum.

Try to use the rectal form of this medicine at a time when you can lie down afterward and hold the medicine in. Avoid using the bathroom during this time.

If you are using bisacodyl before surgery or a medical procedure, follow your doctor's instructions about the timing of your dose (the number of days or hours) before your procedure.

Remove the outer wrapper from the suppository before inserting it. Avoid handling the suppository too long or it will melt in your hands.

Lie on your side and gently insert the suppository pointed end first. For best results, hold in the suppository for a 15 to 20 minutes. The suppository will melt quickly once inserted and you should feel little or no discomfort while holding it in. Avoid using the bathroom just after you have inserted the suppository.

Shake the rectal enema gently just before use. Remove the protective cap from the applicator tip. You may use the enema lying down or seated on a toilet. Gently insert the tip into your rectum and lightly squeeze the bottle to release the enema. Hold the enema in for a few minutes and then release into the toilet.

The rectal forms of bisacodyl should produce a bowel movement within 15 minutes to 1 hour.

The tablet form of bisacodyl should produce a bowel movement within 6 to 12 hours, or overnight when taken at bedtime.

Call your doctor if you do not have a bowel movement after using this medication. Do not use bisacodyl for more than 7 days in a row unless your doctor tells you to. Store bisacodyl at room temperature away from moisture and heat.

What happens if I miss a dose?

Since bisacodyl is used only once or as needed, you are not likely to be on a dosing schedule.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include watery diarrhea, stomach cramps, muscle weakness, or urinating less than usual.

What should I avoid while using Bisco-Lax (bisacodyl)?

Avoid using any other medications within 2 hours before or after using bisacodyl.

Avoid drinking milk within 1 hour after using bisacodyl.

Bisco-Lax (bisacodyl) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

urinating less than usual or not at all;

drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting;

swelling, weight gain, feeling short of breath;

rectal bleeding;

severe stomach pain or cramps, severe or ongoing diarrhea or vomiting; or

low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling).

Less serious side effects may include:

dizziness, weakness;

increased thirst;

mild stomach pain, gas, indigestion;

diarrhea or loose stools;

mild nausea; or

skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Bisco-Lax (bisacodyl)?

There may be other drugs that can interact with bisacodyl. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

More Bisco-Lax resources

Bisco-Lax Side Effects (in more detail)
Bisco-Lax Use in Pregnancy & Breastfeeding
Bisco-Lax Drug Interactions
Bisco-Lax Support Group
0 Reviews for Bisco-Lax - Add your own review/rating

Bisacodyl Prescribing Information (FDA)

Bisacodyl Professional Patient Advice (Wolters Kluwer)

Bisacodyl Monograph (AHFS DI)

Bisacodyl MedFacts Consumer Leaflet (Wolters Kluwer)

Evac-u-gen Chewable Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Bisco-Lax with other medications

Bowel Preparation
Constipation

Where can I get more information?

Your pharmacist can provide more information about bisacodyl.

See also: Bisco-Lax side effects (in more detail)

Vostar-R

Vostar-R may be available in the countries listed below.

Ingredient matches for Vostar-R

Diclofenac

Diclofenac sodium salt (a derivative of Diclofenac) is reported as an ingredient of Vostar-R in the following countries:

Iceland

International Drug Name Search

Friday, 2 July 2010

Flucortis

Flucortis may be available in the countries listed below.

Ingredient matches for Flucortis

Fluticasone

Fluticasone propionate (a derivative of Fluticasone) is reported as an ingredient of Flucortis in the following countries:

Greece

International Drug Name Search

Thursday, 1 July 2010

Acasmul

Acasmul may be available in the countries listed below.

Ingredient matches for Acasmul

Diltiazem

Diltiazem hydrochloride (a derivative of Diltiazem) is reported as an ingredient of Acasmul in the following countries:

Chile

International Drug Name Search

Linc. Oral

Linc. Oral may be available in the countries listed below.

In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Linc. Oral

Lincomycin

Lincomycin hydrochloride monohydrate (a derivative of Lincomycin) is reported as an ingredient of Linc. Oral in the following countries:

Netherlands

International Drug Name Search

Wednesday, 28 July 2010

CLOBEX (clobetasol propionate - lotion; topical)

CLOBEX (clobetasol propionate - shampoo; topical)

CLOBEX (clobetasol propionate - spray; topical)

Has a generic version of Clobex been approved?

clobetasol propionate lotion; topical

clobetasol propionate shampoo; topical

clobetasol propionate spray; topical

Related Patents

See also...

Saturday, 24 July 2010

Ingredient matches for Famotidin-ratiopharm

Thursday, 22 July 2010

Robinul is used for:

Do NOT use Robinul if:

Before using Robinul:

How to use Robinul:

Important safety information:

Possible side effects of Robinul:

If OVERDOSE is suspected:

General information:

More Robinul resources

Compare Robinul with other medications

Introduction

Uses for Docusate Salts

Constipation

Docusate Salts Dosage and Administration

Administration

Oral Administration

Dilution

Rectal Administration

Dosage

Pediatric Patients

Constipation

Oral

Oral, Alternative Dosing (e.g., Liquid Formulations)

Rectal

Adults

Constipation

Oral

Oral, Alternative Dosing (e.g., Liquid Formulations)

Rectal

Special Populations

Hepatic Impairment

Renal Impairment

Geriatric Patients

Cautions for Docusate Salts

Contraindications

Warnings/Precautions

General Precautions

Chronic Use or Overdosage

Use of Fixed Combination

Common Adverse Effects

Interactions for Docusate Salts

GI Drug Absorption

Specific Drugs

Docusate Salts Pharmacokinetics

Absorption

Bioavailability

Onset

Duration

Stability

Storage

Oral

Capsules

Solutions and Syrups

Tablets

ActionsActions

Advice to Patients

Preparations

Comparative Pricing

Disclaimer

References

Wednesday, 14 July 2010

Commonly used brand name(s)

Uses For betaxolol

Before Using betaxolol

Allergies

Pediatric

Geriatric