Saturday, 31 October 2009

Ambroxol acis




Ambroxol acis may be available in the countries listed below.


Ingredient matches for Ambroxol acis



Ambroxol

Ambroxol hydrochloride (a derivative of Ambroxol) is reported as an ingredient of Ambroxol acis in the following countries:


  • Germany

International Drug Name Search

Monday, 26 October 2009

Risperidona Temperbex




Risperidona Temperbex may be available in the countries listed below.


Ingredient matches for Risperidona Temperbex



Risperidone

Risperidone is reported as an ingredient of Risperidona Temperbex in the following countries:


  • Spain

International Drug Name Search

Azatadina




Azatadina may be available in the countries listed below.


Ingredient matches for Azatadina



Azatadine

Azatadina (DCIT) is known as Azatadine in the US.

International Drug Name Search

Glossary

DCITDenominazione Comune Italiana

Click for further information on drug naming conventions and International Nonproprietary Names.

Friday, 16 October 2009

Doribax


Doribax is a brand name of doripenem, approved by the FDA in the following formulation(s):


DORIBAX (doripenem - injectable; iv (infusion))



  • Manufacturer: JANSSEN PHARMS

    Approval date: October 12, 2007

    Strength(s): 500MG/VIAL [RLD]


  • Manufacturer: JANSSEN PHARMS

    Approval date: October 5, 2010

    Strength(s): 250MG/VIAL

Has a generic version of Doribax been approved?


No. There is currently no therapeutically equivalent version of Doribax available.


Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Doribax. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents


Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.




  • Pyrrolidylthiocarbapenem derivative
    Patent 5,317,016
    Issued: May 31, 1994
    Inventor(s): Nishitani; Yasuhiro & Irie; Tadashi
    Assignee(s): Shionogi Seiyaku Kabushiki Kaisha
    A pyrrolidylthiocarbapenem derivative represented by Formula I is provided: ##STR1## wherein R.sup.1 is hydrogen or lower alkyl; R.sup.2, R.sup.3 and R.sup.4 are hydrogen, lower alkyl which can be substituted or an amino protecting group independently, or R.sup.2 and R.sup.3 together with a nitrogen atom to which R.sup.2 and R.sup.3 are bonded form a saturated or unsaturated cyclic group, or R.sup.2 and R.sup.4, or R.sup.3 and R.sup.4 together with two nitrogen atoms and one sulfur atom in the sufamide group form a saturated or unsaturated cyclic group; each cyclic group can further include at least one atom selected from the group consisting of oxygen, sulfur and nitrogen, and each cyclic group can be substituted; X.sup.1 is hydrogen or a hydroxy protecting group; X.sup.2 is hydrogen, a carboxy protecting group, an ammonio group, an alkali metal or an alkaline-earth metal; and Y.sup.2 is hydrogen or an amino protecting group.
    Patent expiration dates:

    • June 5, 2015
      ✓ 
      Patent use: METHOD OF TREATING BACTERIAL INFECTIONS
      ✓ 
      Drug substance
      ✓ 
      Drug product



Related Exclusivities

Exclusivity is exclusive marketing rights granted by the FDA upon approval of a drug and can run concurrently with a patent or not. Exclusivity is a statutory provision and is granted to an NDA applicant if statutory requirements are met.

  • Exclusivity expiration dates:
    • October 12, 2012 - NEW CHEMICAL ENTITY

See also...

  • Doribax Consumer Information (Drugs.com)
  • Doribax Consumer Information (Wolters Kluwer)
  • Doribax Consumer Information (Cerner Multum)
  • Doribax Advanced Consumer Information (Micromedex)
  • Doribax AHFS DI Monographs (ASHP)
  • Doripenem Consumer Information (Wolters Kluwer)
  • Doripenem Consumer Information (Cerner Multum)
  • Doripenem Intravenous Advanced Consumer Information (Micromedex)
  • Doripenem AHFS DI Monographs (ASHP)

Tuesday, 13 October 2009

Doxyseptin




Doxyseptin may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Doxyseptin



Doxycycline

Doxycycline hyclate (a derivative of Doxycycline) is reported as an ingredient of Doxyseptin in the following countries:


  • Switzerland

  • United Kingdom

International Drug Name Search

Sensodyne




Sensodyne may be available in the countries listed below.


Ingredient matches for Sensodyne



Strontium-89 Chloride

Strontium Chloride Sr 89 is reported as an ingredient of Sensodyne in the following countries:


  • Canada

  • Turkey

International Drug Name Search

Monday, 12 October 2009

Vicard




Vicard may be available in the countries listed below.


Ingredient matches for Vicard



Terazosin

Terazosin hydrochloride (a derivative of Terazosin) is reported as an ingredient of Vicard in the following countries:


  • Austria

International Drug Name Search

Sunday, 11 October 2009

Progevera




Progevera may be available in the countries listed below.


Ingredient matches for Progevera



Medroxyprogesterone

Medroxyprogesterone 17α-acetate (a derivative of Medroxyprogesterone) is reported as an ingredient of Progevera in the following countries:


  • Spain

International Drug Name Search

Benicar HCT


Generic Name: hydrochlorothiazide and olmesartan (HYE droe KLOR oh THYE a zide and ol me SAR tan)

Brand Names: Benicar HCT


What is Benicar HCT (hydrochlorothiazide and olmesartan)?

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.


Olmesartan is in a group of drugs called angiotensin II receptor antagonists. Olmesartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.


The combination of hydrochlorothiazide and olmesartan is used to treat high blood pressure (hypertension).


Hydrochlorothiazide and olmesartan may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Benicar HCT (hydrochlorothiazide and olmesartan)?


You should not use this medication if you are allergic to olmesartan or hydrochlorothiazide (Carozide, Diaqua, Ezide HCTZ, HydroDiuril, Microzide, and others), or if you are unable to urinate. Do not use this medication without telling your doctor if you are pregnant. Hydrochlorothiazide and olmesartan may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Avoid drinking alcohol. It can lower your blood pressure and may increase some of the side effects of hydrochlorothiazide and olmesartan. In rare cases, hydrochlorothiazide and olmesartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have muscle pain, tenderness, or weakness especially if you also have fever, nausea or vomiting, and dark colored urine.

What should I discuss with my healthcare provider before taking Benicar HCT (hydrochlorothiazide and olmesartan)?


You should not use this medication if you are allergic to olmesartan or hydrochlorothiazide (Carozide, Diaqua, Ezide HCTZ, HydroDiuril, Microzide, and others), or if you are unable to urinate.

To make sure you can safely take hydrochlorothiazide and olmesartan, tell your doctor if you have any of these other conditions:


  • kidney disease;

  • liver disease;


  • glaucoma;




  • congestive heart failure;




  • low or high levels of potassium in your blood;




  • asthma or allergies;




  • high cholesterol or triglyceride levels;




  • gout;




  • lupus;




  • diabetes; or




  • an allergy to sulfa drugs.




FDA pregnancy category D. Do not use this medication if you are pregnant. Stop using this medication and tell your doctor right away if you become pregnant. Olmesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control while taking hydrochlorothiazide and olmesartan. Hydrochlorothiazide and olmesartan can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using hydrochlorothiazide and olmesartan.

How should I take Benicar HCT (hydrochlorothiazide and olmesartan)?


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.


Your doctor may occasionally change your dose to make sure you get the best results.


Take this medication with a full glass (8 ounces) of water.

Your blood pressure will need to be checked often. Visit your doctor regularly.


Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medication, which can lead to severely low blood pressure or a serious electrolyte imbalance.

Hydrochlorothiazide can interfere with the results of a thyroid test. Tell any doctor who treats you that you are using this medication.


Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. If you need surgery, tell the surgeon ahead of time that you are using hydrochlorothiazide and olmesartan. You may need to stop using the medicine for a short time. Store at room temperature away from moisture and heat.

See also: Benicar HCT dosage (in more detail)

What happens if I miss a dose?


Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include fast or slow heartbeat, feeling light-headed, or fainting.


What should I avoid while taking Benicar HCT (hydrochlorothiazide and olmesartan)?


Drinking alcohol can further lower your blood pressure and may increase certain side effects of hydrochlorothiazide and olmesartan.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.


Do not use potassium supplements or salt substitutes while you are taking hydrochlorothiazide and olmesartan, unless your doctor has told you to.

Benicar HCT (hydrochlorothiazide and olmesartan) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. In rare cases, hydrochlorothiazide and olmesartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine. Call your doctor at once if you have any other serious side effects, such as:

  • eye pain, vision problems;




  • feeling like you might pass out;




  • chest pain, feeling short of breath, even with mild exertion;




  • fever;




  • swelling, rapid weight gain;




  • urinating less than usual or not at all;




  • jaundice (yellowing of the skin or eyes); or




  • dry mouth, increased thirst, drowsiness, restless feeling, confusion, increased urination, fast heart rate, feeling light-headed, fainting, or seizure (convulsions).



Less serious side effects may include:



  • stomach pain, heartburn, diarrhea;




  • joint pain;




  • dizziness, spinning sensation;




  • headache; or




  • dry cough.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Benicar HCT (hydrochlorothiazide and olmesartan)?


Tell your doctor about all other medicines you use, especially:



  • any other diuretic (water pill);




  • any other blood pressure medications;




  • steroids (prednisone and others);




  • lithium (Eskalith, Lithobid);




  • cholestyramine (Prevalite, Questran) or colestipol (Colestid);




  • insulin or diabetes medicine you take by mouth;




  • a barbiturate such as butabarbital (Butisol), secobarbital (Seconal), pentobarbital (Nembutal), or phenobarbital (Solfoton), and others;




  • aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others;




  • a muscle relaxer such as baclofen (Lioresal), carisoprodol (Soma), cyclobenzaprine (Flexeril), dantrolene (Dantrium), metaxalone (Skelaxin), or methocarbamol (Robaxin), orphenadrine (Norflex), or tizanidine (Zanaflex); or




  • a narcotic medication such as hydrocodone (Lortab, Vicodin), meperidine (Demerol), methadone (Methadose), oxycodone (OxyContin), propoxyphene (Darvon, Darvocet), and others.



This list is not complete and other drugs may interact with hydrochlorothiazide and olmesartan. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Benicar HCT resources


  • Benicar HCT Side Effects (in more detail)
  • Benicar HCT Dosage
  • Benicar HCT Use in Pregnancy & Breastfeeding
  • Drug Images
  • Benicar HCT Drug Interactions
  • Benicar HCT Support Group
  • 10 Reviews for Benicar HCT - Add your own review/rating


  • Benicar HCT Prescribing Information (FDA)

  • Benicar HCT Advanced Consumer (Micromedex) - Includes Dosage Information

  • Benicar HCT MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Benicar HCT with other medications


  • High Blood Pressure


Where can I get more information?


  • Your pharmacist can provide more information about hydrochlorothiazide and olmesartan.

See also: Benicar HCT side effects (in more detail)


Friday, 9 October 2009

Potasion Solucion




Potasion Solucion may be available in the countries listed below.


Ingredient matches for Potasion Solucion



Potassium Glucoheptonate

Potassium Glucoheptonate is reported as an ingredient of Potasion Solucion in the following countries:


  • Spain

International Drug Name Search

Thursday, 1 October 2009

dalfopristin and quinupristin


Generic Name: dalfopristin and quinupristin (dal FOE pris tin and kwi NYOO pris tin)

Brand Names: Synercid


What is dalfopristin and quinupristin?

Dalfopristin and quinupristin is a combination antibiotic that fights severe or life-threatening infection caused by bacteria.


Dalfopristin and quinupristin is used to treat severe infections in the blood and other body systems.


Dalfopristin and quinupristin may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about dalfopristin and quinupristin?


You should not receive this medication if you are allergic to dalfopristin and quinupristin.

Before receiving dalfopristin and quinupristin, tell your doctor if you have liver or kidney disease, or a history of any type of allergy.


Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.


What should I discuss with my health care provider before receiving dalfopristin and quinupristin?


You should not receive this medication if you are allergic to dalfopristin and quinupristin.

If you have certain conditions, you may need a dose adjustment or special tests to safely receive this medication. Before you receive dalfopristin and quinupristin, tell your doctor if you are allergic to any drugs, or if you have:



  • liver disease;




  • kidney disease; or




  • a history of any type of allergy.




FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether dalfopristin and quinupristin passes into breast milk or if it could harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.

How is dalfopristin and quinupristin given?


Dalfopristin and quinupristin is given as an injection through a needle placed into a vein. Your doctor, nurse, or other healthcare provider will give you this injection.


Dalfopristin and quinupristin is most often given in a hospital setting. The medicine must be given slowly through an IV infusion, and can take up to 1 hour or longer to complete.


Dalfopristin and quinupristin is usually given for at least 7 days, or longer for more severe infections.


What happens if I miss a dose?


Since this medicine is usually given in a hospital, it is not likely that you will miss a dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

Overdose can cause vomiting, trouble breathing, tremors, shaking, and loss of balance or coordination.


What should I avoid while taking dalfopristin and quinupristin?


Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.


Dalfopristin and quinupristin side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

  • diarrhea that is watery or bloody;




  • jaundice (yellowing of the skin or eyes);




  • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;




  • confusion, seizure (convulsions);




  • feeling light-headed, fainting;




  • pale skin, easy bruising or bleeding, unusual weakness; or




  • fever, chills, body aches, flu symptoms.



Less serious side effects may include:



  • joint or muscle pain;




  • mild skin rash or itching;




  • nausea, vomiting, constipation;




  • headache, dizziness;




  • sleep problems (insomnia);




  • vaginal itching or discharge; or




  • pain, swelling, or irritation where the IV needle is placed.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Dalfopristin and quinupristin Dosing Information


Usual Adult Dose for Skin or Soft Tissue Infection:

Complicated: 7.5 mg/kg IV every 12 hours, infused over 1 hour

Usual Adult Dose for Bacteremia:

Vancomycin-resistant Enterococcus faecium infection: 7.5 mg/kg IV every 8 hours, infused over 1 hour

This indication is no longer approved by the FDA. The submitted data failed to confirm clinical benefit for this condition.

Usual Pediatric Dose for Skin or Soft Tissue Infection:

Less than 12 years: Data not available
12 to less than 18 years: 7.5 mg/kg IV every 12 hours, infused over 1 hour


What other drugs will affect dalfopristin and quinupristin?


Before receiving dalfopristin and quinupristin, tell your doctor if you are using any of the following drugs:



  • cisapride (Propulsid);




  • digoxin (digitalis, Lanoxin);




  • diazepam (Valium) or midazolam (Versed);




  • methylprednisolone (Medrol, Duralone, Medipred, and others);




  • cyclosporine (Gengraf, Neoral, Sandimmune), tacrolimus (Prograf);




  • cancer medications such as vinblastine (Velban), vincristine (Oncovin), vinorelbine (Navelbine), docetaxel (Taxotere), paclitaxel (Taxol);




  • a calcium channel blocker such as diltiazem (Cartia, Cardizem), felodipine (Plendil), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others;




  • HIV or AIDS medications such as delavirdine (Rescriptor), indinavir (Crixivan), nevirapine (Viramune), or ritonavir (Norvir); or




  • heart rhythm medications such as disopyramide (Norpace), lidocaine, or quinidine (Quinaglute, Quinidex).



This list is not complete and there may be other drugs that can interact with dalfopristin and quinupristin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.



More dalfopristin and quinupristin resources


  • Dalfopristin and quinupristin Dosage
  • Dalfopristin and quinupristin Use in Pregnancy & Breastfeeding
  • Dalfopristin and quinupristin Drug Interactions
  • Dalfopristin and quinupristin Support Group
  • 0 Reviews for Dalfopristin and quinupristin - Add your own review/rating


Compare dalfopristin and quinupristin with other medications


  • Bacteremia
  • Methicillin-Resistant Staphylococcus Aureus Infection
  • Skin Infection


Where can I get more information?


  • Your doctor or pharmacist can provide more information about dalfopristin and quinupristin.